Pharmacology and Toxicology of Major Constituents of Marijuana—On the Metabolic Activation of Cannabinoids and Its Mechanism
نویسندگان
چکیده
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 578
منابع مشابه
Effect of Cannabinoid Receptor Activation on Spreading Depression
Objective(s) The objective of this study was to evaluate the effect of cannabinoid on cortical spreading depression (CSD) in rat brain. Cannabis has been used for centuries for both symptomatic and prophylactic treatment of different types of headaches including migraine. CSD is believed to be a putative neuronal mechanism underlying migraine aura and subsequent pain. Materials and Methods T...
متن کاملChemical Constituents, Antimicrobial, Cytotoxicity, Mutagenic and Antimutagenic Effects of Artemisia ciniformis
The aim of this study was to determine the chemical constituents, antimicrobial, cytotoxicity, mutagenic and anti-mutagenic activities of the essential oil of Artemisia ciniformis Krasch. & Popov ex Poljakov, against important bacterial pathogens and human cells which were unknown before. In vitro cytotoxicity was measured using a modified MTT assay on normal human lymphocytes and tumor HeLa ce...
متن کاملAnti-invasion Effects of Cannabinoids Agonist and Antagonist on Human Breast Cancer Stem Cells
Studies show that cancer cell invasion or metastasis is the primary cause of death inmalignancies including breast cancer. The existence of cancer stem cells (CSCs) in breast cancermay account for tumor initiation, progression, and metastasis. Recent studies have reporteddifferent effects of cannabinoids on cancer cells via CB1 and CB2 cannabinoid receptors. In thepresent study, the effects of ...
متن کاملA review of the effects of Berberis vulgaris and its major component, berberine, in metabolic syndrome
Metabolic syndrome (MetS), characterized by a cluster of metabolic abnormalities including hypertension, obesity, type 2 diabetes mellitus (T2DM) and dyslipidemia, is a well-known cardiovascular risk factor (CVRF). Cardiovascular disease (CVD) represents a massive healthcare burden worldwide. In recent years, with regard to the adverse effects of synthetic drugs, increasing attention has been p...
متن کاملAnti-invasion Effects of Cannabinoids Agonist and Antagonist on Human Breast Cancer Stem Cells
Studies show that cancer cell invasion or metastasis is the primary cause of death inmalignancies including breast cancer. The existence of cancer stem cells (CSCs) in breast cancermay account for tumor initiation, progression, and metastasis. Recent studies have reporteddifferent effects of cannabinoids on cancer cells via CB1 and CB2 cannabinoid receptors. In thepresent study, the effects of ...
متن کامل